Regenerative Injection Therapy
PRP, viscosupplementation, and biologic therapies — all delivered under ultrasound or fluoroscopy guidance to ensure precise anatomical placement and maximize therapeutic effect.
Harnessing Your Biology to Heal Damaged Tissue
Regenerative injection therapy leverages the body's own growth factors, signaling proteins, and biologic scaffolds to promote tissue healing, reduce chronic inflammation, and restore function in damaged joints, tendons, ligaments, and cartilage. Unlike corticosteroids — which suppress inflammation but do not address the underlying tissue damage — regenerative approaches aim to shift the tissue environment toward repair.
At Silver Spring Medical Center, every regenerative injection is performed under real-time ultrasound or fluoroscopic imaging, ensuring that biologic agents are deposited precisely at the site of pathology — not approximated by external landmarks.
Platelet-Rich Plasma (PRP)
- Prepared from the patient's own blood via centrifugation protocol
- High platelet yield (4–7× baseline concentration)
- Leucocyte-rich formulations preferred for tendon and soft tissue
- Growth factors: PDGF, TGF-β, VEGF, IGF — stimulate tissue repair
- Indications: tendinopathy, osteoarthritis, ligament tears, muscle injuries
Viscosupplementation
- Hyaluronic acid injection for knee, hip, shoulder, and ankle OA
- Restores synovial fluid viscosity and joint lubrication
- Reduces friction on remaining cartilage surfaces
- 1–5 injection series depending on product used
- All injections performed under image guidance for verified intra-articular placement
Biologics & Emerging Therapies
- Alpha-2-macroglobulin (A2M) for cartilage protection
- Bone marrow aspirate concentrate (BMAC) — when indicated
- Amniotic membrane allografts — anti-inflammatory, anti-fibrotic
- All therapies selected based on evidence, tissue type, and severity
Who Is a Good Candidate?
- Failed or partial response to corticosteroid injections
- Tendinopathy unresponsive to PT and eccentric exercise
- Mild-to-moderate OA not yet requiring joint replacement
- Desire to avoid or delay surgical intervention
- Active individuals seeking tissue-level recovery, not suppression
PRP Quality & Preparation at SSMC
Not all PRP is the same. Platelet concentration, leukocyte content, activation method, and delivery accuracy all determine clinical outcomes. At SSMC, we use a standardized double-spin protocol with documented platelet yield, and select leucocyte-rich or leucocyte-poor formulations based on the target tissue. Every injection is confirmed under live imaging — because a perfectly prepared PRP product injected to the wrong location does nothing.
- ~30cc whole blood draw
- Double-spin centrifugation for maximum platelet yield
- Target: 4–7× baseline platelet concentration
- Leucocyte-rich: tendon, fascia, soft tissue
- Leucocyte-poor: intra-articular cartilage applications